Responsibilities:
1. Design and optimize synthetic routes for pharmaceutical intermediates, active pharmaceutical ingredients (APIs), and novel drug candidates. Conduct comprehensive literature research, develop scientifically rigorous synthetic protocols aligned with cutting-edge industry technologies and project objectives, and ensure the feasibility, cost-effectiveness, and safety of all synthetic pathways.
2. Independently perform end-to-end synthetic experiments, covering raw material preparation, reaction execution, product isolation & purification, and structural characterization. Accurately record raw experimental data (including reagent loadings, reaction temperature and duration, product yield, purity, etc.) and conduct structural confirmation of synthesized products.
3. Troubleshoot technical issues arising during experiments — such as low reaction conversion, substandard product purity, and excessive side reactions. Develop and validate corrective solutions through literature analysis and systematic reaction condition screening.
4. Organize and analyze biological activity assay data of synthesized molecules, and summarize structure-activity relationships (SAR).
5. Strictly adhere to laboratory safety regulations and environmental compliance requirements. Operate all laboratory instruments and equipment per standard operating procedures (SOPs) and perform routine maintenance. Contribute to the improvement of the laboratory R&D management system and the documentation & retention of technical expertise.
Qualifications:
1. Master’s degree or higher in Organic Chemistry, Medicinal Chemistry, Pharmaceutical Chemical Engineering, Applied Chemistry, or a closely related scientific discipline.
2. 1–3 years of organic synthesis R&D experience in the pharmaceutical industry is preferred; prior work experience at top-tier pharmaceutical companies or professional research institutions / CROs is highly preferred.
3. Solid theoretical expertise in organic synthesis and medicinal chemistry, with a proven ability to independently design synthetic routes and resolve complex technical challenges. Proficient in operating a full range of laboratory instruments; capable of precise experimental data analysis and technical report drafting. Strong capabilities in literature retrieval and analysis, with fluent reading comprehension of English scientific literature. Excellent communication and coordination skills, a strong teamwork mindset, and robust project execution ability.
4. Rigorous scientific approach, high sense of accountability, and strong ability to work under pressure to meet R&D project timelines. Strict compliance with intellectual property (IP) policies, with a commitment to safeguarding R&D materials and core proprietary technologies. Alignment with the company’s corporate culture, genuine passion for pharmaceutical R&D, and demonstrated willingness and capacity for continuous professional growth.
